LymphedemaV1, Main, Exploration, bibRecord, 000402

MYC amplification in angiosarcomas arising in the setting of chronic lymphedema of morbid obesity.

Identifieur interne : 000402 ( Main/Exploration ); précédent : 000401; suivant : 000403

MYC amplification in angiosarcomas arising in the setting of chronic lymphedema of morbid obesity.

Auteurs : David Harker [États-Unis] ; Michael Jennings [États-Unis] ; Patrick Mcdonough [États-Unis] ; Melissa Mauskar [États-Unis] ; Stephanie Savory [États-Unis] ; Gregory A. Hosler [États-Unis] ; Travis Vandergriff [États-Unis]

Source :

Journal of cutaneous pathology [ 1600-0560 ] ; 2017.

RBID : pubmed:27686553

Descripteurs français

KwdFr :
- Adulte d'âge moyen, Amplification de gène, Femelle, Humains, Hémangiosarcome (), Hémangiosarcome (génétique), Lymphoedème (étiologie), Maladie chronique, Obésité morbide (), Protéines proto-oncogènes c-myc (génétique), Technique FISH, Tumeurs cutanées (), Tumeurs cutanées (génétique).
MESH :
- génétique : Hémangiosarcome, Protéines proto-oncogènes c-myc, Tumeurs cutanées.
- étiologie : Lymphoedème.
- Adulte d'âge moyen, Amplification de gène, Femelle, Humains, Hémangiosarcome, Maladie chronique, Obésité morbide, Technique FISH, Tumeurs cutanées.

English descriptors

KwdEn :
- Chronic Disease, Female, Gene Amplification, Hemangiosarcoma (complications), Hemangiosarcoma (genetics), Humans, In Situ Hybridization, Fluorescence, Lymphedema (etiology), Middle Aged, Obesity, Morbid (complications), Proto-Oncogene Proteins c-myc (genetics), Skin Neoplasms (complications), Skin Neoplasms (genetics).
MESH :
- chemical , genetics : Proto-Oncogene Proteins c-myc.
- complications : Hemangiosarcoma, Obesity, Morbid, Skin Neoplasms.
- etiology : Lymphedema.
- genetics : Hemangiosarcoma, Skin Neoplasms.
- Chronic Disease, Female, Gene Amplification, Humans, In Situ Hybridization, Fluorescence, Middle Aged.

Abstract

Angiosarcoma is a malignancy of vascular endothelial cells which may arise secondarily as a complication of lymphedema, including chronic lymphedema of morbid obesity. Amplifications in MYC are frequently present in secondary angiosarcoma (arising in irradiated sites and chronic lymphedema) and less frequently in primary cutaneous angiosarcoma.

DOI: 10.1111/cup.12827
PubMed: 27686553

Affiliations:

Le document en format XML

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<author><name sortKey="Harker, David" sort="Harker, David" uniqKey="Harker D" first="David" last="Harker">David Harker</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, TX, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, TX</wicri:regionArea>
<placeName><region type="state">Texas</region>
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<author><name sortKey="Jennings, Michael" sort="Jennings, Michael" uniqKey="Jennings M" first="Michael" last="Jennings">Michael Jennings</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Chronic Disease</term>
<term>Female</term>
<term>Gene Amplification</term>
<term>Hemangiosarcoma (complications)</term>
<term>Hemangiosarcoma (genetics)</term>
<term>Humans</term>
<term>In Situ Hybridization, Fluorescence</term>
<term>Lymphedema (etiology)</term>
<term>Middle Aged</term>
<term>Obesity, Morbid (complications)</term>
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<term>Hémangiosarcome (génétique)</term>
<term>Lymphoedème (étiologie)</term>
<term>Maladie chronique</term>
<term>Obésité morbide ()</term>
<term>Protéines proto-oncogènes c-myc (génétique)</term>
<term>Technique FISH</term>
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<term>Obesity, Morbid</term>
<term>Skin Neoplasms</term>
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<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Hemangiosarcoma</term>
<term>Skin Neoplasms</term>
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<term>Protéines proto-oncogènes c-myc</term>
<term>Tumeurs cutanées</term>
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<term>Gene Amplification</term>
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<term>Hémangiosarcome</term>
<term>Maladie chronique</term>
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<front><div type="abstract" xml:lang="en">Angiosarcoma is a malignancy of vascular endothelial cells which may arise secondarily as a complication of lymphedema, including chronic lymphedema of morbid obesity. Amplifications in MYC are frequently present in secondary angiosarcoma (arising in irradiated sites and chronic lymphedema) and less frequently in primary cutaneous angiosarcoma.</div>
</front>
</TEI>
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<tree><country name="États-Unis"><region name="Texas"><name sortKey="Harker, David" sort="Harker, David" uniqKey="Harker D" first="David" last="Harker">David Harker</name>
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<name sortKey="Hosler, Gregory A" sort="Hosler, Gregory A" uniqKey="Hosler G" first="Gregory A" last="Hosler">Gregory A. Hosler</name>
<name sortKey="Jennings, Michael" sort="Jennings, Michael" uniqKey="Jennings M" first="Michael" last="Jennings">Michael Jennings</name>
<name sortKey="Mauskar, Melissa" sort="Mauskar, Melissa" uniqKey="Mauskar M" first="Melissa" last="Mauskar">Melissa Mauskar</name>
<name sortKey="Mcdonough, Patrick" sort="Mcdonough, Patrick" uniqKey="Mcdonough P" first="Patrick" last="Mcdonough">Patrick Mcdonough</name>
<name sortKey="Savory, Stephanie" sort="Savory, Stephanie" uniqKey="Savory S" first="Stephanie" last="Savory">Stephanie Savory</name>
<name sortKey="Vandergriff, Travis" sort="Vandergriff, Travis" uniqKey="Vandergriff T" first="Travis" last="Vandergriff">Travis Vandergriff</name>
</country>
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Serveur d'exploration sur le lymphœdème

MYC amplification in angiosarcomas arising in the setting of chronic lymphedema of morbid obesity.

MYC amplification in angiosarcomas arising in the setting of chronic lymphedema of morbid obesity.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
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